Drug/Food interactions- Incompatibility of dairy foods with systemic fluoride has occured due to formation of calcium fluoride, which is poorly absorbed

Eczema, atopic dermatitis, urticaria, allergic rash. Gastric distress, headache, weakness. Rinses and gel containing stannous fluoride may produce surface staining of the teeth.

When the fluoride content of drinking water exceeds 0.7ppm, low sodium or sodium free diets, hypersens to fluoride Special precautions: Fractures. Mucositis, tartrazine sensitivity

Indications:

Preventension of dental carriers

Dosage:

Use as per directions .

1. Milk and other dairy products may decrease absorption of sodium fluoride; avoid simultaneous ingestion

Pharmacology:

Sodium fluoride acts systematically before tooth eruption and topically posteruption by increasing tooth resistence to acid dissolution, by promoting remineralisation and by inhibiting the cariogenic microbial process.

Pharmacokinetics:

Fluoride is absorbed in the GItract, lungs and skin. About 90% of the oral fluoride is absorbed in the stomach. Following ingestion, 50% of the fluoride is deposited in bone and teeth. Major route of excrtetion is the kidneys.

Incompatibility of dairy foods with systemic fluoride has occured due to formation of calcium fluoride, which is poorly absorbed

Pregnancy:

Consult physician before using

Lactation:

Consult physician before using

Children:

Do not use 1mg tabs in children below 3 years old and when the drinking water fluoride content is more than 0.3ppm.