Drug Interaction:
Fluoroquinolones include the following : Ciprofloxacin, Norfloxacin, Lomefloxacin, Ofloxacin, Pefloxacin, Enoxacin
Refer Ciprofloxacin
Interacting drugs -summary
Sparfloxacin +
Antacids-
Al and Mag decr antacids contg. Al and Mg reduce bioavailibity of sparfloxacin
Digoxin-
Digoxin levels in plasma may increase
Indication:
Respiratory tract infection, Genito-urinary infection, Skin and soft tisssue infection
Fluoroquinolones include the following : Ciprofloxacin, Norfloxacin, Lomefloxacin, Ofloxacin, Pefloxacin, Enoxacin, Moxifloxacin, Sparfloxacin Gatifloxacin, Nadifloxacin
Refer Ciprofloxacin
New Drugs Approved by (DCI) Drug Controller GENERAL - India For Marketing
(Ref- IDMA Publication)
Name of Drug Indication Date of Approval
Sparfloxacin Comunity acquired 11-11-1996
Pneumonia acute exacerbation
of chronic bronchitis, other lower
gonococcal and non gonococcal
Burethritis in complicated U.T.I
Adverse Reaction:
Diarrhoea, abdominal pain, Nausea, vomiting, Anorexia,, stomatitis,
Thirst, constipation. Jaundice, renal failure, Elevation of liver enzymes. BUN and creatinine. Cutaneous allergy,
Pyrexia, anaphylactoid reaction, Headache, dizziness,
Convulsions, tremors, Myalgia, rhabdomyolysis, Thrombocytopenia and eosinophilia.
Contra-Indications:
Hypersensitivity, pregnancy and lactation, children.
Special precautions:
Elderly patients, patients with a history of epilepsy, severe renal dysfunction.
Dosages/ Overdosage Etc:
Indication
Respiratory tract infection, Genito-urinary tract infection, Skin and soft tissue infection
Dosage
The dosage range varies from 100mg to 400mg once daily after food.
The duration of theapy varies from 5 to 10 days.
Other Information:
For Availability/supplies
Contact -
1.Indian Drug Manufacturers Association (IDMA)
Phone- 022- 24944624/ 24974308
Fax- 022- 24950723
Email- idma@vsnl.com
Website: www.idma-assn.org
2.Bulk Drug Manufacturers Association (India)(BDMA)
Phone - 040-23703910/ 23706718
Fax- 040-23704804
Email- info@bdmai.org
Website: www.info@bdmai.org
Patient Information:
Refer fluoroquinolones
AVOID CONCURRENT USE WITH ERYTHROMYCIN
Pharmacology/ Pharmacokinetics:
Refer fluroquinolones
Interaction with Food:
No interaction with food
Pregnancy and lactation:
Use contraindicated Observe caution if required to be used during pregnancy and lactation
Manufacturer Details