None reported

Gallstone dissolution

GI- abdominal pain/discomfort, nausea, vomiting, diarrhea, anorexia, loose stool, indigestion.
Fever, leukopenia, pruritus, fatigue/lethargy, intolerance, chills, depression

 

Impaired hepatic function, significant biliary tract infection, history of recent duodenal ulcer  


Special precautions:
Rate of administration, intended for biliary tract perfusion only, not for parentral use. Pregnancy, lactation, children

 

Indications:
Gallstone dissolution

Dosage-

Gallstones must be radiolucent and readily accessible to the profusate

Add 13ml of sterile water for injection to each 120ml vial to reduce the viscocity and enhance the bathing of stones

The drug should enter the body temp at 37 C and be maintained at this temp during admin.

 

Pharmacology:
Monooctanoin is a semisynthetic esterified glycerol intended for cholestrol dissolution  via theperfusion of the common bile duct. Monoactanoin is readily hydrolysed by pancreatic and other digestive lipases.

 

Not applicable

Pregnancy:
Use during pregnancy only when clearly needed.

Lactation:
Excercise caution while administering to a nursing woman.

Children:
Safety and efficacy for use in children have not been established.