Gemcitabine Hcl 20mg/ml inj,
List of Related Indications:
List Of Drugs:
- Gemcitabine Hcl- @-Gemzar (1996,2004 and 2014)- Antineoplastics- (FDC-List )
Indication Type Description:
Dosages/ Overdosage Etc
Pregnancy and lactation
Antineuoplastic agents include-
Interferon ALFA 2a, Interferon ALFA -2b, Interferon ALFA -n3, Levamisole, Altretamine, Cladribine, Hydroxyurea, Aldesleukin, Paclitaxel, Docetaxel,Tretinion, Procarbazine,Dacarbazine, Gemcitabine, Mitotane, Asparaginase, Pegaspargase,Porfimer Sodium
Mild parasthesis, severe paresthesias.
Rash, hair loss. Nausea, vomiting,
Transcient elevations of serum transaminases, Diarrhea, stomatistis.
Dyspnea, severe dyspnea. Mild proteinuria,
Hematuria, hemolytic uremic syndrome.
Perpipheral edema, -flu syndrome -, astenia,
Anorexia, headache, Cough, chills, Myalgia, insomnia, Rhinitis, sweating, Malaise.
Known hypersens to the drug
Patients receiving the drug must be monitored to receiving each dose with a complete blood count. (CBC), including differential count.
Dosages/ Overdosage Etc:
Adrenocarcinoma of pancreas
IV use only Administered IV at a dose of 1000mg/m2 over 30 minutes once weekly for upto 7 weeks, followed by a week of rest from treatment.
Subsequent cycles should consist of infusions once weekly for 3 consecutive weeks out of 4 weeks.
Gemcitabine is a nucleoside analog that exhibits antitumor activity. Gemcitabine exhibits cell phase specificity primarily killing cells undergoing DNA synthesis,and blocking the progression of cells.
The maximum plasma concentrations were acheived upto 30 minutes after discontinuation of the infusions and metabolite is excreted in urine without undergoing further biotransformation.
Pregnancy and lactation: