ENDACE-40
Manufacturer Details
SAMARTH PHARMA
Compositions:
Megestrol acetate 40mg/160mg tablets,
|
Strength
|
Rate
|
Packing Style
|
|
40mg
|
311.60
|
10s tablets
|
|
160mg
|
1095.96
|
10s tablets
|
List of Related Indications:
- Advanced breast cancer
- Endometriosis
List Of Drugs:
- Megestrol acetate -Carcino -Chemotherapeutic drugs- (Dec 2012)
Indication Type Description:
Drug Interaction:
Decreases indinavir levels. May increase insulin requirements
Indication:
Approved by (DCI) Drug Controller GENERAL - India For Marketing
(Ref- IDMA Publication)
Name of Drug Indication Date of Approval
Megesterol Acetate Oral 05-12-2012
Suspension 400mg per 10ml
(10 & 20mg Sachet)
For the treatment of Anorexia, Cachexia, or an unexplained ,
significant weight loss in patients with a diagnosis of cancer or
acquired immunodeficiency syndrome (AIDS)
Decreases indinavir levels.
May increase insulin requirements
Adverse Reaction:
Weight gain, nausea, vomiting
Edema, breakthrough bleeding
Thrombo-embolic disorders
DVT
Adrenal suppression
Heart failure
GI upset, dyspnea,
Lumor flare
Hypertension, hyperglycemia
Mood changes, hot flushes, sweating, rash
Carpal Tunnel syndrome
Contra-Indications:
Pregnancy
Lactation
Special precautions-
History of thrombopheblitis
Severe hepatic impairment
Diabetes ( monitor blood levels )
Dosages/ Overdosage Etc:
Indication-
Palliative treatment of recurrent inoperable or metastatic carcinoma of the breast
Breast cancer -
160mg daily as a single or divided doses
Endometrial cancer -
40 - 320mg daily as divided doses
Both for a minimum period of 2 months
Children- not applicable
Pregnancy and lactation:
Contraindicated for use during pregnancy and lactation .
Observe caution if required to be administered
