Increased nephrotoxicity with cyclosporin

To promote diuresis in acute renal failure.

Fluid and electrolyte imbalance acidosis with high doses nausea, vomiting, thirst, headache, dizziness convulsions, chills, fever, tachycardia

Pulmonary congestion or edema intracranial bleeding CHF, metabolic edema with abnormal capillary fragility Special precautions: Hypervolaemia, urinary tract obstruction check for signs of fluid and electrolyte imbalance Should not be administered with whole blood Pregnancy Lactation

Indications:

To promote diuresis in acute renal failure.

Dosage:

Administer IV infusions only. Individualise dose. Usual dose - 20 to 200g/24 hours. In most cases adequate response acheived with 50 to 100g/24 hours.

Observe caution