SURMONTIL
Manufacturer Details
PIRAMAL HEALTHCARE ( ROCHE)
Compositions:
Trimipramine 10mg/25mg tabs,
|
Strength
|
Rate
|
Packing Style
|
|
10mg
|
0.00
|
Tab
|
|
25mg
|
0.00
|
Tab
|
List of Related Indications:
List Of Drugs:
- Trimipramine - @ Tricyclic
Indication Type Description:
Pharmacology/ Pharmacokinetics
Drug Interaction:
Tricylic Compounds include-
Tertiary amines - Amitriptyline,Clomipramine,Doxepin,Imipramine,Trimipramine
Secondary amines - Amoxipine, Desipramine, Nortriptyline,Portriptyline
Refer - Amitriptyline
Impairs antihypertensive effect with guanethedine,methyl dopa and methanidine. Potentiates hypertension produced by sympathtomimetics with MAOIs. Reduced plasma levels with barbiturates Raised levels with methylphenedate. Alcohol potentiates sedative effect.
Indication:
Depression
Tricylic Compounds include-
Tertiary amines - Amitriptyline,Clomipramine,Doxepin,Imipramine,Trimipramine
Secondary amines - Amoxipine, Desipramine, Nortriptyline,Portriptyline
Refer - Amitriptyline
Adverse Reaction:
Agranulocytosis,thrombocytopenia. Drowsiness,orthostatic hypotension and tachycardia(elderly), Headache,peripheral neuropathy tremor,ataxia,seizures, tinnitus, Confusion/delerium(elderly)
Metallic taste,stomatitis, Gastric irritation, Nausea and vomiting, Allergic skin reactions.
Contra-Indications:
Recent M.I.,cardiac arrhythmias,heart block.
Special precautions:
Mania,severe liver disease,narrow angle glaucoma.
Dosages/ Overdosage Etc:
Indications:
Depression
Dosage:
Adult- initially 50 -75 mg/day in divided doses. Increase if necessary to 150 mg/day. may be given in divided doses or as a single dose at night
Do not exceed 200mg/day . Elderly - initial 50 -75 mg daily increased gradually Max 100mg daily
Patient Information:
Refer- Amitriptyline
Pharmacology/ Pharmacokinetics:
Refer amitriptyline.
Interaction with Food:
Not reported.
Pregnancy and lactation:
Refer amitriptyline
