NSAIDs include- Propionic acid- Fenoprofen, Flurbiprofen, Ibuprofen, Ketoprofen, Naproxen, Naproxen Sodium, Oxaprozin Acetic acids- Diclofenac sodium, Etodolac, Indomethicin, Ketorolac, Nabumetone, Sulindac, Tolmetin Fenamates (anthralic acids) - Meclofenamate, Mefenamic acxid Oxicams- Piroxicam Refer- Ibuprofen

Relief of moderate to pain
Treament of primary dysmenorrhea
Treatment of idiopathic heavy menstrual  loss
Acute and chronic rheumatoid arthiritis and osteoarthiritis


NSAIDs include-
Propionic acid- Fenoprofen, Flurbiprofen, Ibuprofen, Ketoprofen, Naproxen, Naproxen Sodium, Oxaprozin
Acetic acids-  Diclofenac sodium, Etodolac, Indomethicin, Ketorolac, Nabumetone, Sulindac, Tolmetin
Fenamates (anthralic acids) - Meclofenamate, Mefenamic acxid
Oxicams- Piroxicam

Refer- Ibuprofen
 

Warnings-

If diarrhea occurs with mefanamic acid or meclofenamate reduce dosage or temporarily discontinue use.

Relief of moderate to pain
Treament of primary dysmenorrhea
Treatment of idiopathic heavy menstrual  loss
Acute and chronic rheumatoid arthiritis and osteoarthiritis


Mild to modrate pain-  
50mg every 4 to 6 hours. Doses of 100mg may be required for optomal pain relief
Do not exceed daily dose of 400mg

Rheumatoid arthiritis-
Usual dose - 200 to 400mg per day in 3 or 4 equal doses.
Initial dose - initiate at a lower dose increase as needed to improve response
Do not exceed 400mg/day
Improvement may occur in a few days
Optimum benefits may not occur for 2 to 3 weeks

Childen - safety and efficacy in cvhildren  < 14 years not established

NSAIDs include-
Propionic acid- Fenoprofen, Flurbiprofen, Ibuprofen, Ketoprofen, Naproxen, Naproxen Sodium, Oxaprozin
Acetic acids-  Diclofenac sodium, Etodolac, Indomethicin, Ketorolac, Nabumetone, Sulindac, Tolmetin
Fenamates (anthralic acids) - Meclofenamate, Mefenamic acxid
Oxicams- Piroxicam
Refer- Ibuprofen
 

Pharmacology-
Monotherapy  with mefanamic acid and transexamic acid offer a simple therapy to be taken during menses
with reductions in mewnstrual blood loss of 25*35% and 50% respy. To increase the efficcay and and to
utilize complementary mechanisms of actions of mefenamic acid and tranexamic acid, a combination of these drugs
has been indicated in the treatment of menorrhagia, DUB, and bleeding due to IUCD and cervical conization.
 
A combination of mefanamic acid and transexamic acid which act by different mechanisms to target uterine bleeding
providing a better option for the management of abnormal uterine bleeding.