Mitomycin-C 2mg/10mg injection,
List of Related Indications:
List Of Drugs:
- Mitomycin-C ( * ) - @- Antibiotic
Indication Type Description:
Dosages/ Overdosage Etc
Interaction with Food
Pregnancy and lactation
Adenocarcinoma of stomach or pancreas, with other chemotherapeutic agents.
Micro-angiopathic haemolytic anaemia and renal toxicity. Delayed cumulative bone marrow supression, profound leucopenia and thrombocytopenia.
Renal damage, pulmonary reactions, G.I.toxicity, alopecia, fever.
Bone marrow depression and haemorrhagic tendencies,neonates, pregnancy.
Leucopenia, lympocytopenia and ulceration of the mouth. Leakage outside blood vessels causes necrosis. Never to be given i.m. or s.c. Monitor renal function.
Dosages/ Overdosage Etc:
Adenocarcinoma of stomach or pancreas, with other chemotherapeutic agents
Give IV only. Use 20mg/sqm IV as a single dose at 6 or 8 weeks intervals.
Mitomycin selectively inhibits the synthesis of deoxyribonucleic acid (DNA).
Clearance is effected primarily by hepatic metabolism. About 10% of a dose is excreted unchanged in the urine.
Interaction with Food:
Pregnancy and lactation:
Pregnancy: Safety for use on pregnant women is not established.