Drug Interaction:
Alcohol. CNS depressants other antipsychotics.
Aluminium and magnesium containing antacids, sucralfate,
Dopominergics, lithium,
Antihypertensives, drugs that prolong QT interval eg anti-arrhyhmics
Ropinirole, narcotics, analgesics,
I.V.erythromycin, anticholinergic agents.
Indication:
U.S.FDA APPROVED DRUGS FROM 01-01-08 TO 31-12-08
Drug name Indication Date of Approval
204. Levosulpiride Inj 25mg/ml 2ml 26-09-08
For the treatment of depression and schizophrenia
in adults when oral therapy is not possible
260. Levosulpride Injection 25mg/2ml 17-12-08
(Addl.stgth)
For the treatment of different Gastro Intestinal problems
like functional dyspepsia, nausea, vomiting & diabetes
gastroparesis. For the treatment of schizophrenzia and
depression in adults
U.S. FDA APPROVED DRUGS DURING 2007
64. Levosulpiride tablet (25mg) 10-05-07
For GI . problem like fanatical dyspepsia,
nausea,vomiting and diabetes Astroporisis
,
180. Levosulpiride tablet (50mg/100mg) 06-12-07
For depression and schizophrenia in adults
,
Approved by (DCI) Drug Controller GENERAL - India For Marketing
(Ref- IDMA Publication)
Name of Drug Indication Date of Approval
1.Levosulphride inj.25mg/ml,2ml 26-09-2008
For the treatment of depression and sciziphrenia in adults when
oral therapy is not possible
2.Levosulphride tablet 10-05-2007
25mg
For G.I.Problem like fanatical dyspepsia, nausea, vomiting and
diabetic gastroperisis
3.Levosulphride tablet 50mg/100mg 12-06-2007
( Addl.Stgth for addl.Indcn.)
For depression and scizophrenia in adults
4.Levosulpride SR 75mg 19-08-2011
+ Rabeprazole Sodium I.P. (EC.pellets)
20mg capsule
For the treatment of Gastro-osephogeal reflux disease (GERD)
5.Levosulphride ER tablet 27-10-2009
100/150/200mg
For the treatment of depression and scizophrenia in adults
6.Levosulphride injection 25mg/2ml 17-12-2008
( Addl.Stgth.)
For the treatment of different Gastro intestinal problems like
functional dyspepsia, nausea, vomiting, & diabetic Gastroparesis
for the treatment of scizophrenia and depression in adults
Functional dyspepsia
Adverse Reaction:
Hyperprolactinemia, acute dystonias and dyskinesias, akathesia
Parkinsonism, drowsiness, insomnia, arrhythmias,
ECG changes, hypotension, convulsions,
Male sexual dysfunction, raised liver enzymes,
Weight gain, amenorrhoea, gynaecomastia, galactorrhoea,
Rarely tardive dyskinesia, jaundice, neuroliptic malignant syndrome
VTE, convulsions.
Contra-Indications:
Phaeochromocytoma, acute porphyria,
Eplilepsy, maniac states, hyperprolactinaemia,
Mammary dysplasia, malignant mastopathies,
Cardiac impairment, GI bleeding,
Mechanical obstruction or peforation Lactation
Special Precautions/Warnings-
Excited or aggresive patients, renal impairment
Parkinsonism disease Risk factors of QT interval prolongation
VTE or stroke
Elderly, withdraw gradually
May impair ability to drive or operate machinery
Pregnancy
Manufacturer Details