KEFLOR
Manufacturer Details
SUN PHARMA
Compositions:
Cefaclor 250mg CAPSULES,
Cefaclor 125mg per 5 ml SYRUP,
Cefaclor 125mg per 5ml - RDEMIX,
Cefaclor 187mg per 5ml - POWDER FOR SUSPENSION,
Cefaclor 125mg/250mg dis tabs- DISTAB,
|
Strength
|
Rate
|
Packing Style
|
|
250mg
|
288.57
|
6s capsules
|
|
125mg/5ml
|
172.00
|
30ml Syrup
|
|
125mg/5ml
|
181.00
|
30ml Reimix
|
|
187mg/5ml
|
157.00
|
30ml Powder for Suspn
|
|
125mg dt
|
129.00
|
6s tablets
|
|
250mg dt
|
268.00
|
6s Distab
|
List of Related Indications:
- Otitis media
- Skin & soft tissue infection
- Urinary tract infections- UTI
List Of Drugs:
- Cefaclor - Cephalosporins @ - Second generation(Apr 1991)
Indication Type Description:
Pharmacology/ Pharmacokinetics
Drug Interaction:
Drugs covered:
1st generation 2nd generation 3rd generation .
Cephalexin Cefaclor Cefixime Cefadroxil Cefamandole Cefoperazone Cephadrine Cefotoxitin Cefotaxime Cephalothin Cefuroxime Ceftizoxime Cephapirin Cefonicid Ceftriaxone Cefazolin Cefmetazole Ceftazidime Cefotetan Ceftibuten Cefprozil Cefepime Cefpodoxime Loracarbef
Refer Cephalosporins
Potentially nephrotoxic and may enhance nephrotoxicity of Gentamicin & Tobramycin.
Nephrotoxicity potentiated by frusemide & ethacrynic acid.
Probenecid slows tubular excretion,hence can be usefully combined.
Indication:
Lower/upper respiratory tract infection, ottitis media, skin structure infection, urinary tract infections
Drugs covered:
1st generation 2nd generation 3rd generation .
Cephalexin Cefaclor Cefixime Cefadroxil Cefamandole Cefoperazone Cephadrine Cefotoxitin Cefotaxime Cephalothin Cefuroxime Ceftizoxime Cephapirin Cefonicid Ceftriaxone Cefazolin Cefmetazole Ceftazidime Cefotetan Ceftibuten Cefprozil Cefepime Cefpodoxime Loracarbef
Refer Cephalosporins
A second generation drug
Approved by (DCI) Drug Controller GENERAL - India For Marketing
(Ref- IDMA Publication)
Name of Drug Indication Date of Approval
Cefaclor Antibiotic April 1991
Adverse Reaction:
Anaphylactic reaction.
Allergic reactions, pseudomembranous colitis (occasionally) diarrhoea, nausea, vomiting, candidiasis, eosinophillia.
Direct positive coombs test without evidence of haemolytic anaemia can cause difficulties in cross matching blood, or in investigation of infants of mothers treated on this drug.
Transient elevation of serum SGOT/SPT levels.
False positive reaction for urinary glucose.
Contra-Indications:
Known hypersens to cephalosporins/penicillins.
Special precautions:
Penicillin hypersens.
Infants less than 1 month,impaired renal function.
Dosages/ Overdosage Etc:
A second generation drug
Indications:
Lower/upper respiratory tract infection, ottitis media, skin structure infection, urinary tract infections
Dosage:
Usual dosage is 250mg every 8hours. In severe infection or those caused by less susceptible organisms, dosage may be doubled.
Children: Give 20mg/kg/day in divided doses every 8 hours. In serious infections caused by less susceptible organisms, administer 40mg/kg/day, with a maximum of 1g/day.
Storage: Refrigerate suspension after reconstitution. Discard after 14 days.
Other Information:
For Availability/supplies
Contact -
1.Indian Drug Manufacturers Association (IDMA)
Phone- 022- 24944624/ 24974308
Fax- 022- 24950723
Email- idma@vsnl.com
Website: www.idma-assn.org
2.Bulk Drug Manufacturers Association (India)(BDMA)
Phone - 040-23703910/ 23706718
Fax- 040-23704804
Email- info@bdmai.org
Website: www.info@bdmai.org
Patient Information:
Refer cephalosporins
Pharmacology/ Pharmacokinetics:
Refer cephalosporins
Interaction with Food:
Take with or without food
Pregnancy and lactation:
Refer cephalosporins
