Alcohol, CNS depressants, anticonvulsants,anticogulants Antidepressants, Carbamazepine Probenecid. Metoclopramide, Cloestyramine, Bisulphan

Mild to moderate pain

Tolerance, dependence, nausea, vomiting Constipation, dizziness, lightheadeness, Rash, Hepatic changes Abdominal pain Hepatotoxicity, respiratory depression (overdose only) Risk of hepatotoxicity , among chronic heavy alcohol users Sports events - restricted /banned

Active alcoholism Gross hepatic damage Sucidal tendencies, history of drug abuse Afddiction prone persons Special precautions- Impaired renal or hepatic function. Respiratory depression , high doses, prolonged use, sucidal prone persons, Concomittasnt admin of tranquillizers, antidepressants or excessive alcohol use Children Elderly Debilitated Pregnancy, lactation

Indication

Mild to moderate pain

Dosage-

1 tab 3 - 4 times a daily

Contraindicated for use pregnancy and lactation. Use with caution