Betamethasone- It there is a significant systemic absorption , neomycin sulfate may increase the resp depressant effects of neuromuscular blockers

Corticosteroid -reponsive drmastoses with secondary infection

Betamethasone- Prologed use may cause local atrophic changes in the skin eg. thinning , striae and dilatation of superficial blood vessels.

Local skin burning sensation, pruritus, pigmentation changes, allergic contact dermatitis and hypertrichosis.

Opthalmic prepn. Corneal ucleation,increased intraocular pressure, mydriasis, pitosis, epithelial punctate keratitis

Betamethasone-

Hypersensitivity acne vulgaris, perianial & genital pruritus

Primary cutaneous viral infections Not to be used in otitis extrena complicated by ear-drum perforation

Treatment of primary infected skin caused by fungi or bacteria

Primary or secondary infections due to yeast or secondary infections due to pseudomonas or Proteus species

Children below 2 year

Opthmalic preparations - not to be used in patients with glaucoma or hepatis keratitis

Special precautions-

Avoid prolonged treatment as it may lead to systemic corticosteroid effects even without occulsion.

Avoid prolonged excessive appln to the facial areas

Withdraw treatment if there is spread of infection

Risk of glaucoma development if prepn, enter eyes .

Regular monitoring is recommended when used for psoriasis due to treatment tolerance, rebound relapses, generalized pustular psoriasis or systemic toxicity Increased risk of contact sensitization when used for extended period or recurrently

Pregnancy and lactation

Opthalmic preparations- Monitor intraocular pressure, contaract formation of unsuspected infections,

Evaluate treatment if there is no clinical improvement after 7 days Not to be used for undiagnosed red eye

Indication-

Corticosteroid -reponsive drmastoses with secondary infection

Dosage-

Apply 2-3 times a day Usual treatment duration upto 5 days/course