Drugs covered:
1st generation 2nd generation 3rd generation .
Cephalexin Cefaclor Cefixime Cefadroxil Cefamandole Cefoperazone Cephadrine Cefotoxitin Cefotaxime Cephalothin Cefuroxime Ceftizoxime Cephapirin Cefonicid Ceftriaxone Cefazolin Cefmetazole Ceftazidime Cefotetan Ceftibuten Cefprozil Cefepime Cefpodoxime Loracarbef
Refer Cephalosporins
Activity enhanced by aminoglycosides.
Respiratory tract infections
Otitis media Urinary tract infections Skin and structure infections
Anaphylactic reactions.
Pain at injection site.
Hypersensitivity,
GI disturbances, candidiasasis,
Eosinophilla, neutropenia, leucopenia, thrombocytopenia,
Rise in liver enzymes and blood urea.
Positive Coombs test.
Known hypersens to cephalosporins.
Special precautions:
Hypersens to penicillins.
Pseudomembranous colitis.
Early pregnancy. Lactation.
Use glucose oxidase or hexokinase methods for blood or plasma glucose tests, renal failure.
Indication-
Otitis media Urinary tract infections
Skin and structure infections
Dosage-
250mg evey 6 hours or 500mg every 12 hours
Uncomplicated urinary tract infections- 500mg every 12 hours Large doses upto 1g 4 times a day may be given for severe or chronic infections
Refer cephalosporins
Observe caution while administering to pregnant or lactating mothers