AMIDATE INJ *
Manufacturer Details
ABBOTT INC
Abbott Laboratories
Pharmacetical Division
Compositions:
Etomide 2mg/m l inj,
Strength
|
Rate
|
Packing Style
|
2mg/ml
|
0.00
|
Tab
|
List of Related Indications:
- Induction of general anesthesia
List Of Drugs:
- Etomidate- General anesthetics
Indication Type Description:
Pharmacology/ Pharmacokinetics
Indication:
Induction of general anesthesia
Adverse Reaction:
Transceient skeletal muscle movements, transceint venous pain.
Hyperventilation hypotension,apnea of short duration with spontaneous recovery, larygnospasm, hiccoups,snoring.
Contra-Indications:
Hypersens to the drug.
Special precaution:
Pregnancy, lactation.
Dosages/ Overdosage Etc:
Indication:
Induction of general anesthesia
Dosage:
For IV use only. Individualise dose
Adults and children over 1 years- 0.2 to 0.6mg/kg. The usual induction dose is 0.3mg/kg,
injected over 30 to 60 seconds
Pharmacology/ Pharmacokinetics:
Pharmacology:
Etomidate, a nonbarbiturate hypnotic without analgesic activity, has fewer cardiovascular and
respiratory depressants effects than the thiopental sodium.
Pharmacokinetics:
Injection IV produces hypnosis rapidly, usually within 1 minute. Etomidate is rapidly metabolised in the liver. Plasma level of unchanged drug decrease rapidly upto 30 minutes following injection and thereafter more slowly with a half-life of about 75 minutes.
Pregnancy and lactation:
Pregnancy:
Use only when clearly needed.
Lactation:
Use caution while administering to anursing mother.
Children:
afety and effeicacy for use inchildren has not been established.