Contraceptives- Oral include - Ethinyl oestrdiol, norethindione, norgestrel, desogestrel, levonorgesrtrel, medoxyprogesterone, progesterone Refer Progesterone

Anticonvulsants, barbiturates, antibiotics, griseofluvin, hepatic enzyme inducers, activated charcoal, Certain laxatives, anti-HIV protease inhibitors, Anticoagulants.TCADs azole antifungals, St johns wort Cyclospor, tacrolimus, modanafinil, Antidiabetics, antihypertensives, Corticosteroids. selegiline, theophyline Herbal products

Contraceptives- Oral include - Ethinyl oestrdiol, norethindione, norgestrel, desogestrel, levonorgesrtrel, medoxyprogesterone, progesterone Refer Progesterone

Thromboembolism, myocardial infarction,

Cerebrovascular disease, hepatic tumors, Chloasma, weight gain, fluid retention, Mood changes, reduced glucose tolerance,

GI upset,genito-urinaryb changes and or /cancer Breast enlargement and tendrness, Depression, headahe, loss of libido,

Menstrual changes, break through bleeding Irregular vaginal bleeding,

Skin reactions, Hypetension, cardiovascular effects, Contact lens iritation, hepatic impairment

Disturbance of lipid metabolism, Rarely, photosensitivity

Circulatory disorders including thrombotic disorders, Hypertension, lipod disorders. Multiple cardiovascular risk factors, Arterial disease or cerebrovascular accident, Heart disease associated with pulmonary hypertension or risk of embolus

Trancient cerbral ischaemic attacks without headache Valvular heart disease , atrial fubrilation Severe hepatic disease including cholestatic jaundice, hepatitis ( for history ) Abnormal LFTs ( previous 3 months ) Dubin- Johnson syndrome Hepatic tumors Abnormal vaginal bleeding SLE assoiated with previos steroid ( inl. OCs) or pregnancy

Pregnancy. Lactation ( until weaning or for 6 months after birth

Special precaution:

Single cardiovascular or thromboembolic risk factor. Cardiac failure, renal impairment Epilepsy Oestrogen sensitive gynaecological disorders, obesity ( BMI > 30kgm2 )

Diabetes, inf;ammatory bowel disease, severe depression, Sickle -cell disease Varicose veins, gall bladder disease Angioedema, severediarrhea and vomiting Heavy smoking ( > 15 cigerettes /day ) andover 35 years of age

Oral contraception

Dosage-

1 tablet daily at the same time, starting on 1st or 5th day of cycle, without interruption for 21 days followed by 7 day tablet free period

Contraceptives- Oral include - Ethinyl oestrdiol, norethindione, norgestrel, desogestrel, levonorgesrtrel, medoxyprogesterone, progesterone Refer Progesterone

Contraceptives- Oral include - Ethinyl oestrdiol, norethindione, norgestrel, desogestrel, levonorgesrtrel, medoxyprogesterone, progesterone Refer Progesterone

Pregnancy, lactation. Observe caution