CARTIGEN
Brand:
CARTIGEN
Manufacturer:
PHARMED
Manufacturer Details
PHARMED
PHARMED MEDICARE
Pharmed Gardens
Whitefield Road
Bangalore 560 048
pharmed@vsnl.com
Compositions:
Glucosamine sulphate 1500mg tablets,
Glucosamine sulphate 500mg s.g.capsules,
|
Strength
|
Rate
|
Packing Style
|
|
1500mg
|
524.00
|
30s tablets
|
|
500mg
|
437.00
|
30s s.g capsules
|
List of Related Indications:
List Of Drugs:
- Glucosamine sulphate- (FDC- List ) (Sep 2002)
Indication Type Description:
Pharmacology/ Pharmacokinetics
Drug Interaction:
Reports not available
Indication:
New drugs approved For Marketing by Drug Controller General of India(DCGI )
during the period January 1988 to November 2014
(Ref- IDMA Annual Publication 2015)
Name of Drug Indication Date of Approval
Glucosamine Sulphate potassium 03-11-2009
Chloride 500mg
+ Ibuprofen IP 200mg film coated tablets
For the treatment of adult patients with osteoarthiritis of knee
and/or hip joints
FIXED DOSE COMBINATIONS APPROVED BY DCG(I)
FROM JANUARY 1961 TILL NOVEMBER 2014
Name of Drug Indication Date of Approval
Combokit of 1 capsule of Glucosamine Sulphate 500mg+ 30-09-2002
Chondroitin sulphate capsule 400mg
For supportive treatment of osteoporosis in adults
Osteoarthritis Rheumatoid arthritis Tendonitis Bursitis
Adverse Reaction:
Epigastric pain/ tenderness, Heartburn, Diarrhea, and nausea, flushing Dyspepsia, constipation, Abdominal pain, palpitations, Drowsiness Skin reaction Headache Indigestion
Contra-Indications:
Allergy to shell fish Special precautions- diabetic patients, patients on heparin Pregnancy and lactation
Dosages/ Overdosage Etc:
Indication-
Osteoarthritis Rheumatoid arthritis Tendonitis Bursitis
Dosage-
Adult - 500mg 3 to 4 times daily Max dose - 1500mg/day
Pharmacology/ Pharmacokinetics:
Pharmacology:
Glucosamine stimulates cartilage cells to synthesise glycosaminoglcans and proteoglycanone. This essentially means that it has the potential to rebuild the cartilage lost in a joint due to injury or osteoarthritis. MSM is naturally occuring sulfur compound. It is an essential component in making collagen, a primary constitute of cartilage and connective tissue. It acts by increasing the cell wall permeability, enhances tissue pliabilty and encourages the repair of damaged skin, also acts as an antioxidant.
Clinical efficacy:
A systemic cochrane review was conducted to evaluate the effectiveness and toxicity of glucosamine in osteoarthritis. It was found that glucosamine to be superior when compared with placebo and NSAIDs.
Interaction with Food:
Reports not available
Pregnancy and lactation:
Use with caution in pregnant and lactating women.
