Drug Interaction:
Nasal decongestants include-
Arylalkalamine-
Phenylpropanolamine, Pseudoephedrine, Phenylephrine, Epinephrine, Ephedrine, Desoxyephedrine, Irridazolines- Naphazoline, Oxymetazoline, Tetrahydrozoline, Xylomethazoline, Cycloalkyamine- Propylhexedrine Refer Phenylpropanolamine
Indication:
New Drugs Approved by (DCI) Drug Controller GENERAL - India For Marketing (Ref- IDMA Publication)
Name of Drug Indication Date of Approval
Xylometazolline 0.5mg 23-12-2009
+ Ipratropium 0.6mg Nasal spray
For Symptomatic Treatment of Nasal Congestion with Running Nose
(Rhinorrhea)
Nasal decongestants include-
Arylalkalamine-
Phenylpropanolamine, Pseudoephedrine, Phenylephrine, Epinephrine, Ephedrine, Desoxyephedrine, Irridazolines- Naphazoline, Oxymetazoline, Tetrahydrozoline, Xylomethazoline,
Cycloalkyamine-
Propylhexedrine Refer Phenylpropanolamine
Patient Information:
Nasal decongestants include-
Arylalkalamine-
Phenylpropanolamine, Pseudoephedrine, Phenylephrine, Epinephrine, Ephedrine,
Desoxyephedrine,
Irridazolines-
Naphazoline, Oxymetazoline, Tetrahydrozoline, Xylomethazoline,
Cycloalkyamine-
Propylhexedrine
Refer Phenylpropanolamine
Ref - USP PDI Vol II 17th Edition (1997)
XYLOMETAZOLINE -NASAL
1.Allergies-
Tell your doctor if you have ever had any unusual or allergic reaction to
Xylometazoline or any other nasal decongestants. Also tell your healthcare
care professional if you are allergic to any other substances such as foods,
preservatives or dyes.
2.Pregnancy-
Xylometazoline may be absorbed into the body. However, xylometaxoline
has not been reported to cause problems in humans.
3. Breast-feeding-
Xylometazoline may be absorbed into the body.However, xylometazoline.
has not been reported to cause any problems in nursing babies.
4.Children-
Children may be especially sensitive to the effects of xylometazoline.This
may increase the side effects during treatment.
5.Older adults-
There is no specific information comparing use of xylometazoline in the
elderly with use in other age groups.
6. Other medicines-
Tell your doctor if you are using any other prescription or non-prescription
(Over-the counter) OTC medicine.
7. Other medical problems-
The presence of other medical problems may affect the use of xylometazoline.
Make sure you tell your doctor if you have any other medical problems
especially-
Diabetes mellitus -
Heart or blood vessel disease or
High blood pressure - xylometazoline may make the condition worse.
Over active thyroid
Pharmacology/ Pharmacokinetics:
Nasal decongestants include-
Arylalkalamine-
Phenylpropanolamine, Pseudoephedrine, Phenylephrine, Epinephrine, Ephedrine, Desoxyephedrine, Irridazolines- Naphazoline, Oxymetazoline, Tetrahydrozoline, Xylomethazoline, Cycloalkyamine- Propylhexedrine Refer Phenylpropanolamine