Not reported

Not reported

Not reported

Special Precautions:

Pregnancy, lactation, hypersensitivity,renal impairment, people taking piperazine or medicines that include piperazine People who have galactose or lactose intolerance or glucose-galactose malabsorption Caution should be advised in alcoholics. Patients should avoid alcohol consumption Caution while driving/using machinery

Indications:

Seasonal allergic rhinitis, Perrenial allergic rhinitis Chronic idiopathic urticaria

Dosage:

5mg once daily

1.Caution should be advised in alcoholics.

2.Patients should avoid alcohol consumption

3.Caution while driving/using machinery

Pharmacology:

Kevocetrizine binds twice as strongly to histamine H1 receptors in vitro and has a highly consistent and predictable antihistamine action in vivo. Pharmacodynamic studies inn healthy volunteers suggest that levocetrizine has at least the same activity as cetrizine

Pharmacokinetics:

Absorptin: It is rapidly absorbed after oral administration. Metabolism: Poorly metabolised. The metabolic pathways involved are oxidation (hydoxylation, )-dealkylation, N-dealkylation) Protein binding: The protein binding of levocetrizine is 96.1% after 1 hour of administration. Excretion: 85.5% of the oral dose is excreted through urine as unchanged drug and 2.4% as metabolite.

Not reported

Not recommended for use during pregnancy and lactation.

Use with caution.