IREX TAB
Manufacturer Details
MICRO LABS
Compositions:
Sodium Feredetate 231.mg,
Folic acid 1.5mg,
Vitamin B 12 15mcg,
Elemental Zinc 7.5mg tabs,
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Strength
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Rate
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Packing Style
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231.mg
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0.00
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Tab
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List of Related Indications:
List Of Drugs:
- Sodium Feredetate + Folic Acid + Vitamin B12
Indication Type Description:
Pharmacology/ Pharmacokinetics
Drug Interaction:
Sodium Feredetate- None reported
Folic acid- None reported
Vitamin B12- Biaguanides, Para-aminodsalicyclic acid, Ptassium Supplements Cholesstyramines, Colchicine, Neomycin, Ethanol Anticonvulsant Drugs has been found to impair cobalamin reaction.
Indication:
Iron deficiency Anemia
Adverse Reaction:
Nausea, Diarrhoea, Allergic skin rashes Fever
Contra-Indications:
Combination is contraindicated in Untreated cobalamin deficiency,
Pernicous anemia, Malignant diseases,
Anaphylactic reaction and in Tobacco amblyopia
Dosages/ Overdosage Etc:
Indication-
Iron deficiency Anemia
Dosage-
Presentation Sodium Feredetate 231mg ( equiv to 33mg elem iron ) Folic Acid 1.5mg Viamin B12 15mcg tablets.
Pharmacology/ Pharmacokinetics:
Pharmacokinetics-
Sodium Feredetate is in unionized form . It breaks down within the gastrointestinal tract to release elemental iron which is then absorbed. Folic acid rapidly absorbed orally and converted to tetrahydrofolate, the metabolically active form.
About 70-80% of a 2mg oral dose of folic acid is absorbed readily from the gastrointetinal tract. It is well distributed into plasma ( 70%) and extracellular fluid. Excess folic acid is excreted largely in urine in unchanged form. Vitamin B12 is taken orally.
Absotption is dose dependent and at high dose it ispoorly absorbed. Vitamin B12 attaches to transcobalamin II for transport to bone marrow and to the liver for storage. Plasma half- life and protein binding varies with dose.
