Drug interactions -summary

 Magnesium salts +

 Aminoquinolines                                                                                                           absorption and therapeutic effect of aminoquinolines decreased

Malaria 

Headache, dizzinesss GI disturbances, Yellow discoloration of skin, and blue or black pigmenttion of nails may occur after prolonged usuage Psychosis, Exfoliative dermatitis Ocular toxicity

Pregnancy Psoriasis Concurrent admin. of primaquine

Malaria Prophylaxis

Dosage-

600mg a week may be given in divided doses

Treatment- 900mg on first day 600mg on 2nd and 5rd day 300mg on 4th, 5th, & 6th day in divided doses

1. Best taken after meals with a full glass of water, tea or fruit juice , unless otherwise directed by doctor

2. For patients unable to swallow or unable to tolerate bitter taste, the tablets may crushed and mixed with jam, honey or chocolate syrup 3.

Make sure that you take all the food so that you get the full dose of medicine.

Use contraindicated. Observe caution.