COMFORA
Manufacturer Details
SARABHAI PIRAMAL
Compositions:
Pentosan Polysulphate Sodium 100mg caps,
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Strength
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Rate
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Packing Style
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100mg
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0.00
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Tab
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List of Related Indications:
- Cystitis
- Intestinal colic
List Of Drugs:
- Pentosan Polysulphate Sodium - @- Interstitial cystitis agent
Indication Type Description:
Pharmacology/ Pharmacokinetics
Drug Interaction:
Reports not available
Indication:
Relief of bladder pain or discomfort associated with intestinal cystitis
Adverse Reaction:
Commonly reported adverse reactions- diarrhea and headache alopecia and rectal haemorrhage ( 1-.5% )
Contra-Indications:
Contraindicated in patients with known hypersensitivity to the drug
Special precautions-
Patients undergoing invasive procedures or having signs or symptoms of underlying coagulaopathy Increased risk of bleeding should be evaluated for hemorrhage
Caution to be excercised when using PPS in patients who have a history of heparin-induced thrombocytopenia PPS should be given cautiously in patients suffering from hepatic insuficiency or splenic disorders
Dosages/ Overdosage Etc:
Indication-
Relief of bladder pain or discomfort associated with intestinal cystitis
Dosage-
Recommended dose - 300mg/day taken as 100mg caps three times a daily
Patient Information:
1. Patients should take the drug as prescribed. in the dosage prescribed and
no more frequently than prescribed.
2. Patients should be reminded that pentosan polysulfate sodium has a
weak anticoagulant effect. This may increase bleeding times
Pharmacology/ Pharmacokinetics:
Pharmacokinetics-
PPS ia low molecular weight heparin-like sulphated polysaccharide exhibiting anticoagulant and fibrolytic effects.
