Not known

External genital and perianal warts

Adverse reactions leading to discontinuation or dose interrruption was 5%

Local site reactions- erythema, local pain, skin erosion, ulceration, vesicles, dysuria
genital herpes

Dermatological  - bleedding 2%, burning 60%, discharge 3%, erosion/ulceration 45%
eryhthema 65%, pruritus 55%, rash vasicular 20%

Miscellaneous- edema 40%, induration 30%, pain/discomfort 50%

Warning/precautions-

Open wounds- avoid using sinecatechins on open wounds

Immunosuppressed patients- safety and efficacy in immunosuppressed patients have not been established

Photosentivity- advice patients to avoid exposure of the genital and perianal area to sunlight or ultraviolight

Pregnancy- no adequate and well  documented studies in pregnant women. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Lactation- not known if topically applied sinecatachins are excreted  in breast milk.

Children- Safety and efficacy in children have not been established

Indications-

External genital and perianal warts

Dosage-

Apply 3 times per day to all external genital and perianal warts. About 0.5 cms

 strand of the ointment should be applied to each wart using the finger, dabbing it to ensure complete coverage and leaving a thin layer of the ointment on the warts 

1. For external use only.

2. Avoid using sinecatechins on open wounds

3. Avoid exposure of the genital and parianal warts to sun light or UV light

Pharmacology-

The mode of action of sinecatechine ointment invloved in the clearance of genital and perianal warts is unknown

Pregnancy-

No adequate and well  documented studies in pregnant women. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Lactation-

Not known if topically applied sinecatachins are excreted  in breast milk.