TOPHAN
Manufacturer Details
SOMNOGEN
Somnogen Pharmaceuticals Pvt Ltd
Plot No 504 D wing
L B S Nagar
Sion
Mumbai 400 099
Compositions:
Trytophan( 5-hydroxytrytophan) 50mg tablets,
|
Strength
|
Rate
|
Packing Style
|
|
50mg
|
0.00
|
10s tablets
|
List of Related Indications:
List Of Drugs:
- Trytophan - @ - Anti-depressants
Indication Type Description:
Drug Interaction:
Drug interactions- summary-
Increased risk of serotonin with SSRI
Possible decrease in levodopa plasma levels with trytophan
Increased risk of severe behavioural and neurological toxicity with MAOIs
start with lower initial dose of trytophan if needed
Adverse Reaction:
Nausea ( take after food to minimise nausea.)
Headache, lightheaedness , drowsiness, eosionophilia -myalgia syndrome
Contra-Indications:
History of eosinophailia -myalgia syndrome associated with trytophan treatment
Special Precautions-
May affect ability to drive or operate machinery
Monitor for suicadal thoughts or cliniacl worsening of depression during treatment period
Renal or hepatic impairment
Elderly
Dosages/ Overdosage Etc:
Indication-
Depression
Dosage-
Adult- L-Trytophan 1 g tid
Max - 6g
Elderly- dose reduction may be needed
Patient Information:
Take after food to minimise nausea
Interaction with Food:
Take after food to minimise nausea
