COVERSYL- AM
Brand:
COVERSYL- AM
Manufacturer:
SERDIA
Manufacturer Details
SERDIA
Compositions:
,
Perindopril erbumine 4mg + Amlodipine besylate 5mg tablets ,
Perindopril erbumine 4mg + Amlodipine besylate 10mg tablets,
Perindopril erbumine 8mg +Amlodipine besylate 5mg tablets,
Perindopril erbumine 10mg +Amlodipine besylate 10mg tablets,
Strength
|
Rate
|
Packing Style
|
4mg+5mg
|
162.00
|
10s tablets
|
4mg+10mg
|
171.00
|
10s tablets
|
8mg+5mg
|
184.00
|
10s tablets
|
8mg+10mg
|
186.00
|
10s tablets
|
List of Related Indications:
List Of Drugs:
- Perindopril Erbumine + Amlodipine Besilate
Indication Type Description:
Pharmacology/ Pharmacokinetics
Adverse Reaction:
Headache, somloence,
Nausea
Abdominal pain, dyspepsia
Palpitations, dizziness
Contra-Indications:
In children, pregnancy, lacating women
Patients sensitive to the product
Dosages/ Overdosage Etc:
Indication-
Hypertension
Dosage-
I tablet daily at breakfast
Pharmacology/ Pharmacokinetics:
Rationale for combination-
International guidelines have strongly endorsed fixed -dose combinations for first-line and
second line treatment of hypertension
ACE inhibitors and CCB combinaton stand out among recommended combinations for either
complementary mechansims of action which lead to enhanced efficacy
The Anglo-Scandinavian cardiac outcomes Trial Blood Pressure Lowering Arm ( ASCOT- BPLA )
trail demonstrates a significant reduction in risk of cardiovascular and all-cause death, stroke,
coronary events, and procedures, new onset diabetes and new onset renal impairment with
combination with amlodipine and peridopril in a wide range of patients with hypertension.
Amlodipine and perindopril is an ideal evidence based combination in the treatment
of hypertension
Pregnancy and lactation:
Contraindicated in pregnancy and lactation.
Observe caution if use is required.