Patient Information:
Ref - USP PDI Vol II 17th Edition (1997)
OPIUM PREPARATIONS- systemic - Morphine, Codeine, Papavarine
1.Allergies-
Tell your doctor if you have ever had any unusual or allergic reaction to
morphine, codeine, or papaverine. Also tell your healthcare care
professional if you are allergic to any other substances such as foods,
preservatives or dyes.
2.Pregnancy-
Opium preparations has not been studied in pregnant women. However,
morphine has caused birth defects in animals when given in very large doses.
3. Breast-feeding-
Opium preparations have not been studied in pregnant in nursing babies.
4.Children-
Breathing problems may be especially likely to occur in children up to
2 years of age, who are usually more sensitive to the effects of
opium preparations.
5.Older adults-
Breathing problems may be especially likely to occur in elderly patients, who
are usually more sensitive to the effects of opium preparations
6. Other medicines-
Tell your doctor if you are using any of the following -
Anticholinergics ( medicines for staomach spasms or cramps) or
CNS system depresants or
Other diarrhoea medicine or
Tricyclic antidepresants - the chance of side effects increased
Naltrexone- naltrexone blocks the effects of opium preparations
and makes them less effective in treating diarrhea
7. Other medical problems-
Make sure you tell your doctor if you have any other medical problems
especially-
Alcohol or other drug abuse or
Colitis or
Heart disease or
Kidney disease or
Liver disease or
Underactive thyroid - the chance of side effects may be increased
Brain damage or head injury or
Emphysema ,asthma, bronchtis, or other chronic lung disease or
Enlarged prostrate or problems with urination or
Gall bladder disease or gallstone - some of the side effects of
opium preparation can be dangerous if these conditions are
present
Convulsions- seizures- history of- opium can rarely cause
convulsions
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