No known drug interactions with alpha lipoic acid

Diabetic neuropathy

Skin rash, reduced absorption of iron and other minerals may occur.

Hypoglyceamic reported in some diabetic patients

Pregnancy and lactation

Monitor blood glucose regularly

Indication-

Diabetic neuropathy

Dosage-

300 - 600 mg once a daily preferably in an empty stomach.

Take 30 minutes before meals. Swallow whole. Do not chew/crush.

Pharmacology:

Alpha-lipoic acid plays an esstential role in mitochondrial dehydragenenase reactions. Lipoate orits reduced form, dihydrolipoate has been shown toreact with reactive oxygen species such as superoxide radicals, hydroxyl radicals, hypochlorus acid, proxyl radicals and singlet oxygen.

Pharmacokinetics:

Following single administration, an elevation of the maximum blood concentration and an increase of alpha-lipoic acid elimination half-life in patients with liver cirrhosis.

Take 30 minutes before meals. Swallow whole. Do not chew/crush

Use contraindicated. Observe caution