Drug Interaction:
Antidepressants-
Do not use yohimbine
Adverse Reaction:
Yohimbine readily penetrate CNS and produces complex pattern of response in lower doses
than those required to produce peripheral alpha - adrenergic blockade.
These include antidiuresis, and central excitation , including elevated blood pressure and heart
rate, increased motor activity , nervousness, irritability and tremor
Dizziness, nausea, headache, and skin flushing have been reported
Contra-Indications:
Renal disease, hypersensitivity to any component
Special Precautions-
Special risk patients- not for use in geriatric, psychiatric or cardiorenal patients with a history
of duodenal ulcer. Generally not for use in females
Pregnancy- do not use during pregnancy
Lactation- this drug is not proposed for use in females
Children- do not use in children
Dosages/ Overdosage Etc:
Indication-
Impotence
Dosage-
Male erectile impotence-
Experimental dosage- 1 tablet ( 5.4mg ) 3 times/day
Occassional side effects with this dosage are -nausea, dizziness or nervousness
If side effects occur reduce to one half tablets 3 times a day, followed by gradual increase
to 1 tablet 3 times/day
Results of therapy greater than 10 weeks are not known
Patient Information:
Ref - USP PDI Vol II 17th Edition (1997)
YOHIMBINE -SYSTEMIC
1.Allergies-
Tell your doctor if you have ever had any unusual or allergic reaction to
Yohimbine or any of the rauwolfia alkaloids, suc as desrodine, rauwolfia
serpentina or reserpine. Also tell your healthcare care professional
if you are allergic to any other substances such as foods. preservatives or dyes.
2.Older adults-
Although there is no specific information comparing use of yohimbine in the
elderly with use in other age groups, this medicine has been used in some
elderly patients and has not shown to cause different side effects in older
people than younger adults.
3. Other medicines-
Tell your doctor if you are using any other prescription or non-prescription
(Over-the counter) OTC medicine.
4. Other medical problems-
The presence of other medical problems may affect the use of yohimbine.
Make sure you tell your doctor if you have any other medical problems
especially-
Angina pectoris or
Depression or
Other psychiartric illness or
Heart disease or
High blood pressure or
Kidney disease - yohimbine may make these conditions worse.
Liver disease - effects of yohimbine may be increased because
of slower removal from the body
Pregnancy and lactation:
Pregnancy-
Do not use during pregnancy
Lactation-
This drug is not proposed for use in females
Children-
Do not use in children
Manufacturer Details