Drug Interaction:
Corticosteroids topical include-
Alcometasone dipropionate, Amcinonide, Betamethasone benzoate, dipropionate, valerate, Clobetasol propionate, clocortolone pivalate, Desonide, Desoximetasone, Dexamethasone, Diflorasone, Fluocinolone acetonide,Fluocinonide, Flurandrenolide, Fluticasone propionate, Halcinode, Halobetasol Propionate, Hydrocortisone, Methylprednisolone acetate, Mometasone furoate, Prednicarbate, Triamcinolone acetonide
Refer - Betamethasone
Indication:
LIST OF DRUGS DURING 2006
Sr.No- 83
Name of the Drug- Clobestasol Proppianat (0.05% )+
Calcipotriol Ointment (0.005%) Ointment Pharmacological Classification- Plaque pseuriasis
Date of Approval- 20-07-2006
Approved by U.S.FDA on 30-12-2006 (Ref- FDA approved List)
New drugs approved For Marketing by Drug Controller General of India(DCGI )
during the period January 1988 to November 2014
(Ref- IDMA Annual Publication 2015)
Name of Drug Indication Date of Approval
Clobetatasol propionate 0.05% + 20-07-2006
Calcipotriol ointment 0.005% ointment
For plaque psoariasis
FIXED DOSE COMBINATIONS APPROVED BY DCG(I)
FROM JANUARY 1961 TILL NOVEMBER 2014
Name of Drug Indication Date of Approval
1.Clobestasol Propionate 0.05% + 20-07-2008
Calcipotriol ointment 0.005% ointment
2.Clobetasol Propionate 0.05% w/w+ 07-08-1996
Ammonium Lactate 12% w/w gel
Dry hyper- keratotic steroid responsive dermatoses inflammatory
manifestations of psoriasis (excluding wide spread plague psoriasis)
Relief of inflammatory and pruritic manifestations of corticosteroid- responsive dermatoses
Corticosteroids topical include-
Alcometasone dipropionate, Amcinonide, Betamethasone benzoate, dipropionate, valerate, Clobetasol propionate, clocortolone pivalate, Desonide, Desoximetasone, Dexamethasone, Diflorasone, Fluocinolone acetonide,Fluocinonide, Flurandrenolide, Fluticasone propionate, Halcinode, Halobetasol Propionate, Hydrocortisone, Methylprednisolone acetate, Mometasone furoate, Prednicarbate, Triamcinolone acetonide
Refer - Betamethasone
Adverse Reaction:
Use of large amounts of clobetasol propionate over very large areas of the body can lead to sufficient systemic absorption to produce adrenal suppression.
Cushings syndrome diabetes and hypertension.
Perioral dermititis, striae especially in flexures.
Dermal & epidermal atrophy especially on the face, steroid purpura.
Contra-Indications:
Not recommended for children below 12 years.
Risasea, acne vulgaris, perioral dermatitis.
Primary cutaneous viral infections.
Lesions infected with bacteria or fungi.Hypersens.
Special precautions:
In long therpy evaluate for evidence of HPA axis supression. Discontinue if irritation occurs. Should not enter eyes.
If infection exists, treat with specific anti-infectives.
Dosages/ Overdosage Etc:
For plaque psoariasis
Indication-
Relief of inflammatory and pruritic manifestations of corticosteroid- responsive dermatoses
Dosage-
Apply sparingly to affected areas 2 to 4 times daily
Other Information:
For Availability/supplies
Contact -
1.Indian Drug Manufacturers Association (IDMA)
Phone- 022- 24944624/ 24974308
Fax- 022- 24950723
Email- idma@vsnl.com
Website: www.idma-assn.org
2.Bulk Drug Manufacturers Association (India)(BDMA)
Phone - 040-23703910/ 23706718
Fax- 040-23704804
Email- info@bdmai.org
Website: www.info@bdmai.org
Patient Information:
Refer - Betamethasone
Pharmacology/ Pharmacokinetics:
Refer topical corticosteroids
Interaction with Food:
Not applicable
Pregnancy and lactation:
Refer topical corticosteroids
Manufacturer Details