ARICEP
Brand:
ARICEP
Manufacturer:
EISAI
Manufacturer Details
EISAI
Eisai Pharmaceuticals India Pvt .Ltd
1st Floor, B- wing,
Marwah Centre
Kishnial Marwah Marg
Andheri East
Mumbai 400 072
Compositions:
Donepezil 5mg/10mg tablets,
|
Strength
|
Rate
|
Packing Style
|
|
5mg
|
114.00
|
10s tablets
|
|
10mg
|
162.75
|
10s tablets
|
List of Related Indications:
List Of Drugs:
- Donepezil-Neurodegenerative disease drugs (Mar -2001)
Indication Type Description:
Drug Interaction:
May increase the neurotoxic effect of antipsychotics. Concurrent use with systemic corticosteroids may increase the adverse effects of donepezil May increase the neuromuscular blocking effect of succinyl choline. May increase the advese effects of cholinergic agonists. May increase the bradycardic effect of betablockers
Indication:
Alzheirmers disease
Approved by (DCI) Drug Controller GENERAL - India For Marketing
(Ref- IDMA Publication)
Name of Drug Indication Date of Approval
1.Donepezil Hcl For Alzheirmers dimentia 23-03-2001
2. Donepezil HCl 15-10-2009
Orodispersible Tablet 5mg/10mg
For the treatment of mild to moderate severe Alzheimers Dimentia
Adverse Reaction:
Nausea, vomting, anorexia, Weight loss, insomnia, fatigue, Muscle cramps, headache, dizziness, Syncope, bradycardia, Convulsions, Increased liver transaminase, sinoatrial and atrioventricular block, Hallucinations, agitation, aggressive behaviour Minor increases in plasma creatinine kinase, Potentially bladder outflow obstruction
Contra-Indications:
Hypersensitivity Special precautions-
Caution when used in patients with sick sinus syndrome or cardiac conduction abnormalities May increae secretion of gastric acid.
Caution when used in patients at risk of ulcer disease Patients with COPD asthma History of epilepsy, bladder obstruction, prostrate hypertrophy May cause dose related diarrhoea, nausea, and or vomiting which usually resolves after 1-3 weeks Safety and efficacy not established in children Pregnancy Lactation
Dosages/ Overdosage Etc:
For the treatment of mild to moderate severe Alzheimers Dimentia
Mild to moderate dimentia
Adult- initially 5mg at bedtime, increase if necessary up to 10mg once daily at bed time. after 4-6 weeks
Elderly- initially 5mg daily at bed time, increase if necessary up to 10mg once daily at bed time after 4-6 weeks
Pregnancy and lactation:
Contraindicated for use during pregnancy and lactation Observe caution if required to be used during this period
