Brand Information

Strength	Rate	Packing Style
2%w/w	95.00	5g cream

Drug Interaction:

Mixing of mupirocin ointment with oral preparations may dilute mupricon content and lead to reduction of antibacterial activity.

Indication:

LIST OF DRUGS DURING 2007

Sr.No- 160

Name of the Drug- Mupirocin 2% +

Methylprednisolone Acetonate (0.2%) cream Pharmacological Classification- For atopic dermatitis

Date of Approval- 31-10-07

Approved by U.S.FDA on 30-12-2007 (Ref- FDA approved List- 2007)

Eradication of nasal colonisation with staphy aures

Approved by (DCI) Drug Controller GENERAL - India For Marketing

(Ref- IDMA Publication)

Name of Drug Indication Date of Approval

1.Mupirocin September 1991

Anti- bacterial skin infection

2.Mupirocin 2% 31-010-200

+Methylprednisolone acetonate

0.1% creram

For atopic dermatitis

Adverse Reaction:

Burning, stinging, pain, itching, erythema, dryness, tenderness,

Rarely contact dermatitis and rash.

Contra-Indications:

Hypersens.to mupirocin or ployethylene glycol

Special precauitions:

Mucosal surfaces of the eye, renal impairment( with polythene glycol), pregnancy, lactation.

Dosages/ Overdosage Etc:

Indications:

Eradication of nasal colonisation with staphy aures

Dosage:

Apply small amount of affected area 3 times a day.

Patient Information:

Ref - USP PDI Vol II 17th Edition (1997)

1.Allergies-

Tell your doctor if you have ever had any unusual or allergic reaction to

mupirocin. Also tell your healthcare care professional if you are allergic

to any other substances such as foods. preservatives or dyes.

2.Pregnancy-

Toipcal mucirocin has not been studied in pregnant women. However,

this medicine has not been shown to cause birth defects or other problems

in animal studies

3. Breast-feeding-

It is known whether topical mucpirocin passes into breast milk. However, this

medicine is unlikely to pass into breast milk in large amounts.

since very little is absorbed into mothers body when applied to the skin.

4.Children-

There is no specific information comparing use of topical mupirocin

in children with use in other age groups.

5.Older adults-

There is no specific information comparing use of topical mupirocin

in the elderly with use in other age groups

6. Other medicines-

Tell your doctor if you are using any or /other prescription or

non-prescription (Over-the counter) OTC medicine that is

applied to the same area of skin.

Pharmacology/ Pharmacokinetics:

Pharmacology:

Mupirocin , a topical antibacterial structurally unrelated to other agents, is produced by fermentation of the organism pseudomononas fluorescens. Mupirocin inhibits bacterial protein synthesis by reversibly and specicifically binding to bacterial isoleucyl transfer-RNA syntheesis.

Pregnancy and lactation:

Pregnancy:

Use only if needed.

Lacation:

Temporarily discontinue nursing while using mupirocin

I-BACT

Drug Interaction

Indication

Adverse Reaction

Contra-Indications

Dosages/ Overdosage Etc

Patient Information

Pharmacology/ Pharmacokinetics

Pregnancy and lactation