In vivo studies have shown that precipitation occurs when eye drops containing thiomerosal are mixed with latanoprost.

If such drugs are used administer with an interval of at least minutes between applications.

Common systemic adverse events seen with latanoprtost were upper respiratory tract infection/cold/flu. pain in muscle/joint/back, chest pain/angina pectoris.

Hypersens to the drug

Special precautions: Cornea, bacterial keratitis.

Contact lens- do not administer while wearing contact lenses

Indication-

Open angle glaucoma

Dosage- One drop in the affected eye once daily in the evening Latanoprost may used concomittantly with other topical products to lower IOP.

1. Advise patients about the possibility of iris color change because of an increase of the brown pigment and resultant cosmetically different eye coloration that may occur.

2. Remove contact lens prior to admin. Com\ntact lens may be reinserted after 15 minutes following latanoprost admin.

3. If more than one topical opthalmic drug is being used, administer the drugs at least 5 minutes apart.

Pharmacology:

Latanoprost is a prostaglandin analog that is beleved to reduce the IOP by increasing the outflow of aqueous humor.

Pregnancy:

Use only if required

Lactation:

Excercise caution while administering latanoprost to nursing mothers.