Adverse Reaction:
Headache, irritability, restlessness, depression, Fatigue, oedema, percocious puberty, Gynaecomastia, pain at injection site, Aggressive behaviour, ovarian hyperstimulation syndrome, Ovarian malignancy, enlargement of ovarian cysts, and possible rupture, and arterial thrombo-embolism.
Contra-Indications:
Precocious puberty, prostatic carcinoma or other androgen-dependent neoplasm, prior allergic reaction to chorionic gonadotropin, pregnancy & lactation
Special precautions:
Precocious puberty- Induction of androgen secretion by HCG may induce phatalic enlargement.
Fluid retension-
use with caution in patients with epilepsy, migraine, asthma, cardiac or renal disease.
Patient Information:
Chorionic Gonadotropin - systemic
1.Allergies-
Tell your doctor if you are have ever had any unusual or allergic reaction to
chorionic gonadotropin. Also tell your healthcare care professional if you are
allergic to any other substances such as foods. preservatives or dyes.
2.Pregnancy-
If you become pregnant as a result of using this medicine with menotropins
(eg Pergonal) or urofollitropin ( eg Metrodin) there is an increased chance
of a multiple pregnancy (eg twins, triplets)
3.Children-
Chorionic gonadotropin when used for treatment cryptorchidism ( a birth defect
where the testes remain inside the body) has caused the sexual organs of
some male children to develop too rapidly.
4. Other medicines-
Although certain medicines should not be used together at all, in other cases two
different medicines may be used together even if an interaction might occur.
In such cases your doctor may want to change the dose, or other precautions
may be necessary.
Tell your doctor if you are using any other prescription or non-prescription
(Over-the counter) OTC medicine.
5. Other medical problems-
The presence of other medical problems may affect the use of chorionic
gonadotropin . Make sure you tell your doctor if you have any other medical
problems especially-
Cancer of the prostrate - increases in the amount of testosterone in the
bloodstream may make this condition worse.
Cyst on overy or
Fibroid tumors of the uterus- chorionic gonadotropin can cause the pitutiary
gland or a pitutiary tumor to increase in size
Unusual vaginal bleeding - irregular vaginal bleeding is a sign that the
endometrium is growing too much, of endomterial cancer, or other hormone
imbalances, the increase in estrogen production caused by ovalution can
agravate these problems of the endometrium. It other hormone imbalances
are present they should be treated before beginning ovulation induction.