Brand Information

METOLAR -XR

Brand:
METOLAR -XR

Manufacturer:
CIPLA

Compositions:
Metoprolol 12.5mg/25mg/50mg/100mg capsules,

Strength	Rate	Packing Style
12.5mg	71.87	10s capsules
25mg	67.87	15s capsules
50mg	97.08	15s capsules
100mg	185.00	10s capsules

List of Related Indications:

Hypertension

List Of Drugs:

Metoprolol @ ( *** ) - Beta- Adrenergic blocker- (FDC- List )- (Oct 1982)

Indication Type Description:

Drug Interaction

Indication

Adverse Reaction

Contra-Indications

Dosages/ Overdosage Etc

Patient Information

Pharmacology/ Pharmacokinetics

Interaction with Food

Pregnancy and lactation

Indication:

U.S FDA APPROVED DRUGS FROM 01-01-08 TO 31-12-08

Drug name Indication Date of Approval

47. Metoprolol Succinate Equiv. to 28-01-08

Metoprolol Tatrate (ER 25/50mg

+ Atorvastatin (as calcium) 10mg tablets

For the treatment of patient with both essential

hypertension and hypercholestelemia

157. Metoprolol ER 16-07-08

+ Amlodipine tablets

(Addl.Indication)

180. S-Metoprolol Succinate Oral Solution 19-08-08

(Each MI contains;

S-Metaprolol Succinate 9.5mg equal to

S-Metoprolol Tartrate 10mg)

For the treatment of haemodynamically stably

patients with definite or suspected acute Myocardial

Infarction to reduce cardio-vascular mortality

U.S.FDA APPROVED DRUGS DURING 2006

12. Metoprolol Succinate equiv.to 07-02-2006

Metoprolol Tartrate 50mg +

Amlodipine (as besylate) 5mg For Hypertension 151. Metoprolol succinate 25mg ER + 30-11-2006

HCTZ 12.5mg

Anti hypertensive

20. Metoprolol (as succinate 50mg/25mg ER)+ 20-02-07

Amlodipine 5mg/2.5mg tablet

(Addl.stgth)

Angina pectoris in adults

27. Metoprolol (as succinate)ER 25mg/50mg+ 26-02-07

Ramipril 2.5mg/5mg

Essential hypertension

55. Metoprolol (as succinate) 25mg+ 10-04-07

Amlodipine (as besylate) 5mg

(addl.stgth)

as approved

Approved by (DCI) Drug Controller GENERAL - India For Marketing (Ref- IDMA Publication)

Name of Drug Indication Date of Approval

1.Metoprolol Succinate 25mg 10-04-2007

+ Amlodipine Besylate 5mg

( Addl.Stgth.)

As approved

2.Metoprolol succinate 20-02-2007

50mg/25mg ER

+ Amlodipine 5mg/2.5mg tablet

(Addl.Indication)

Angina pectors in adults

3.Metoprolol Succinate ER 26-02-2007

25mg/50mg

+ Ramipril 2.5mg/5mg

Essential hypertension

4.Metoprolol 50/50/25mg 01-07-2009

+ Atorvastatin 20/10/10mg

+ Ramipril 10/5/2.5mg capsules

As 2nd line treatment of patients with both essential hypertension and

Hypercholesterolema who are not adequately controlled by combination

of an Anti-hypertensive with lipid lowering agent

5. Metoprolol ER 16-07-2008

+ Amlodipine Tablets

( Addl.Indtn.)

For coronary artery disease /ischemic herat disease

6.Metoprolol succinate 0.7-02-2006

equiv. to Metoprolol tartrate 50mg

+ Amlodipine Besylate 5mg

For hypertension

7.Metoprolol Succinate 25mg/50mg ER 30-11-2006

+ HCTZ 12.5mg

Anti-hypertensive

8.Metoprolol Succinate 28-01-2008

equiv.to Metoprolol tartrate (ER 25.50mg)

+ Atorvastatin Calcium 10mg tabets

For the treatment of patients with both essential hypertension and

hypercholesterleromia

9. Metoprolol Succinate ER 25/50mg 16-07-2010

+ Telmisartran 20/40mg

For thetreatment of essential hypertension

10. Metoprolol Succinate ER 25/50mg 19-07-2010

+ Olmetsartan 20/20mg

For the treatment of Essential Hypertension

11. Metoprolol Tartrate ER Tablet 75mg 03-10-2009

(Addl.stgth.)

same as approved

12. Metoprolol Tartrate 50mg 14-01-2009

(Addl. indication)

Adjunct to the treatment of Hyperthyroidism

13. Each Film coated tablet contains- 13-04-2009

Metoprolol 25mg/50mg

+ Chlorthalidone 12.5mg

For the treatment of patients with mild to moderate essential hypertension

14. Each film coated tablet contains- 25-04-2009

Metoprolol 25mg/50mg

+ Chlorthalidone 6,25mg/12.5mg

Addl.stgth

Same as approved

15.S(-) Metoprolol succinate 25mg 16-05-2007

+ S(-) Amlodipine Besylate 2.5/5mg

For essential hypertension

16.S(-) Metoprolol Succinate eq. to 07-10-2010

S(-) Metoprolol Tartarate 25mg/50mg

+ Clopidogrel (IR) 75mg/75mg tablet

For the treatment of Essential hypertension who need Antiplatelet

Therapy especially for prophylaxis of atherombotic event

17.S(-) Metoprolol 25mg/50mg ER 04-01-2010

+ Atorvastatin IR 10mg tablets

For the treatment of Patients with both essential Hypertension and

Hypercholestrolemia

18.S-Metoprolol Succinate Oral Solution 19-08-2008

Each ml contains -

S-Metoprolol Succinate 9.5mg

equal to S-Metoprolol Tartarate 10mg

For the treatment of Haemo-Dynamically Stably Patients with definite

or Suspected acute Myocardial infarction to reduce Cardio-Vascular

Mortality

FIXED DOSE COMBINATIONS APPROVED BY DCG(I)

FROM JANUARY 1961 TILL NOVEMBER 2014

Name of Drug Indication Date of Approval

1.FDC of S-Metoprolol Succinate Tartrate 11-11-2005

eq.to Metoprolol 20mg/40mg/40mg+

HCTZ 12.5mg/12.5mg/25mg

For essential hypertension

2.Metoprol 25mg/50mg+ 13.04-2009

Chlorthalidone 12.5/12.5mg

film coated bilayerd tablet

For the treatment of patients with mild to moderate

essential hypertension

3.Metoprolol 25mg/50mg + 25-04-2009

Chlorthalidone 6.25mg/12.5mg

film coated bilayered tablet

Addl.stgth

For the treatment of patients with mild to modrate

essential hypertension

4. Metoprolol 50mg + June 1989

HCTZ 12.5mg tablet

5. Metoprol succinate 25mg/50mg ER + 30-11-2006

HCTZ 12.5mg tablets

Anti hypertensive

6. Metoprolol succinate 02-007-2006

equiv. to Metoprolol tartarate 50mg +

Amlodipine besylate 5mg

For hypertension

7. Metoprolol succinate ER 25mg + 20-12-2011

Telmistratan 40mg tablet

For the treatment of essential hypertension

8.Metoprolol tartrate 100mg + Oct -1982

hydroclorthiazide 12.5mg

9.S(-) Metoprolol Succinate SR tablets eq.to 15-04-2005

S(-) Metoprolol Tartrate 12.5mg/25mg/50mg

For hypertension

10.S(-) Metoprolol 25mg/50mg ER + 11-11-2005

HCTZ 12.5mg/12.5mg IR tablets

For the treatment of mild to moderate hypertension

in adults

11.S(-) Metoprolol 25mg/50mg ER + 01-04-2010

Atotvastatin IR 10mg tablets

For the treatment of patients with both essential

hypertension and hypercholesterolemia

Hypertension

Beta-adrenergic blockers include-

Atenolol, Acebutol, Betaxolol, Bisoprolol,Cartelol,Esmolol,
Labetatol,Metoprolol, Nadolol,Penbutolol, Pinodol, Propranolol, Solatol, Timolol,

Refer - Atenolol

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METOLAR -XR

Drug Interaction

Indication

Adverse Reaction

Contra-Indications

Dosages/ Overdosage Etc

Patient Information

Pharmacology/ Pharmacokinetics

Interaction with Food

Pregnancy and lactation

Drug Interaction:

Indication:

Adverse Reaction:

Contra-Indications:

Dosages/ Overdosage Etc:

Patient Information:

Pharmacology/ Pharmacokinetics:

Interaction with Food:

Pregnancy and lactation:

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