Drug Interaction:
Loop diuretics include- Furosemide, Bumetamide, Ethacrynic acid, Torasemide Refer Furosemide
Indication:
Approved by FDA in August, 1993
LIST OF DRUGS DURING 2007
Sr.No- 2
Name of the Drug- Torsemide 10mg +
Amiloride 5mfg tablets
Pharmacological Classification- Edema associated with congestive heart failure &
hypertension
Date of Approval- 17-01-07
Approved by U.S.FDA on 30-12-2007 (Ref- FDA approved List- 2007)
New Drugs Approved by (DCI) Drug Controller GENERAL - India For Marketing
(Ref- IDMA Publication)
Name of Drug Indication Date of Approval
1.Torasemide Diuretic 09-06-2003
2.Torasemide 10mg 17-01-2007
+Amiloride 5mg Tablets
Edema Associated with Congestive Heart Failure and Hypertension
Diuretic
Adverse Reaction:
Torsemide
CNS- headache, dizziness, asthenia, insomnia, nervousness, syncope GI- diarrhea, constipation, nausea, dyspepsia, edema, GI hemorrhage, rectal bleeding
Cardiovascular- ECG abnormality, sore throat, chest pain, artial fibrillation, hypotension, ventricular tachycardia, shunt thrombosis
Respiratory- rhinitis, cough increase
Musculoskeletal- arthalgia, myalgia
Lab test abnormalities- hyperglycemia, hyperuricemia, hypokalemia,hypovolumia
Miscellaneous- excessive urination.
Contra-Indications:
Refer Furosemide
Dosages/ Overdosage Etc:
Approved by FDA in August, 1993
Diuretic
Dosage:
Torsemide may be given any time in relation to a meal.
CHF: Initial dose is 10 to 20mg once daily oral or IV. If the diuretic response is inadequate, titrate the dose upward by approximately doubling until the desired response is acheived.
Chronic renal failure- Initial dose is 20mg once daily oral or IV. If the diuretic response is inadequate, titrate the dose upward by approximately doubling until the desired response is acheived.
Patient Information:
Loop diuretics
1. May cause GI upset, take with food or milk
2. Drug will increase urination, take early in the day
3. Notify physician if muscle weakness , cramps, nausea, or dizziness occur
4. Orthostatic hypotension may occur, get up slowly
5. Diabetes mellitus patients- may increase blood glucose levels, affecting urine glucose tests.
6. Photosentivity may occur in some patients. Cution patients to take protective measures (ie Sunscreens, protective clothing) against exposure to ultraviolet light or sunlight
7. Hypersensitivity patients should avoid medications that may increase blood pressure, including OTC products for appetite suppression and cold symptoms
Pregnancy and lactation:
Refer Furosemide
Manufacturer Details