APLEVANT
Brand:
APLEVANT
Manufacturer:
LUPIN
Manufacturer Details
LUPIN
Compositions:
Dulaglutide 0.75mg/1mg per 0..5ml 0.5ml injection/ 1.5mg per 0.5ml injection,
|
Strength
|
Rate
|
Packing Style
|
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0.75mg per 0.1ml
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2499.00
|
Pre-filled pen injection
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1.5mg per
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2499.00
|
Pre-filled pen
|
List of Related Indications:
- Type II Diabetes not respons to diet
List Of Drugs:
- Dulaglutide- Antidiabetic drug
Indication Type Description:
Drug Interaction:
Drugs affected by change in gastric emptying, dipeptidyl peptidase 4 inhibitors
Indication:
Type II diabetes inadequately controlled by diet and excercise
Adverse Reaction:
Hypoglycemia, anorexia, nausea, diarrhea, vomiting, abdominal pain, decreased appetite,
dyspepsia, acute pancreatisis, fatigue, sinus tachycardia, 1st degree AV block
Contra-Indications:
Diabetes ketoacidosis, e nd stagee renal disease (egfr < 15ML/MIN/1.73m2)
Severe GI disease, History of ( personal or family) medulliary thyroid carcinoma,
Multiple endocrine neoplasia syndrome type 2
Pregnancy,lactation
Special Precautions
Risk of pancreatitis, advice patient of symptoms, discontinue if suspected
CHF - elderly(>75years) . Monitor renal functions in renally impaired reporting severe GI reactions. History of angioedema or anaphylaxis
Dosages/ Overdosage Etc:
Type II diabetes inadequately controlled by diet and excercise
Dosage
Monotherapy- 750mg by s.c. injection once weekly
Add on therapy- 1.5mg by s.c. iniection once weekly
Combination therapy- consider lower lowewr dose orf sulfonyl urea/insulin
Below 18 years- Not recommended
