ACENOMAC
Manufacturer Details
MACLEODS
Compositions:
Acenocoumarol 1mg/2mg/3mg/4mg tablets,
Strength
|
Rate
|
Packing Style
|
1mg
|
49.50
|
10s tablets
|
2mg
|
82.50
|
10s tablets
|
3mg
|
93.00
|
10s tablets
|
4mg
|
91.00
|
10s tablets
|
List of Related Indications:
- Thrombo-embolic conditions
List Of Drugs:
- Acenocoumarol - Anticoagulant
Indication Type Description:
Drug Interaction:
Potentiates hypoglycemic agents
Bismuth catbonate & Mg reduce absorption
Cimetidine , allopurinol , diuretics, and other oral antocoagulants enhance effect. Vit K reverses effect.
Potentiated by NSAIDs , amiodarone, antibacterial agents eg. co-trimoxazole, cephalosporin, eryhthromycn, quinolone antibiotics, chloramphenicol, doxycycline, INH and neomycin
Rifsampicin ,barbiturates and griseofluvin reverses effect.
Indication:
Thromboembolic disorders
Adverse Reaction:
Alopecia,fever, nausea, vomting, diarrhoea, skin rash, cholestatic jaundice, Liver damage, Haemorrhage
Contra-Indications:
Active hemorhage or risk of serious hemorrhage
Severe hypertension
Special precaution
Bleeding disorders, peptic ulcers, severe wounds,
Cerebral vascular disorders
Bacterial endocarditis
Renal or hepatic impairment
Lactation Avoid alcohol
Dosages/ Overdosage Etc:
Indication
Thromboembolic disorders
Dosage
Adult- 4-12 mg on the ist day and 4-8mg on the second day
Maintenance - 1 -8mg daily given as a single dose at the same time every day
Patient Information:
Special Precaution-
Patient with severe heart failure, knon or suspected protein C or Vitamin K defeciency. Mild to moderate hepatic & renal impairment
Pregnancy and lactation:
Use caution when administering to pregnant and lactating mothers