AMACE
Manufacturer Details
SYSTOPIC
Compositions:
Amlodipine 5mg+ Enalapril 5mg tablets,
|
Strength
|
Rate
|
Packing Style
|
|
5mg+ 5mg
|
65.00
|
10s tablets
|
List of Related Indications:
List Of Drugs:
- Amlodipine + Enalapril maleate
Indication Type Description:
Drug Interaction:
Indomethicin and other NSAIDs may blunt antihypertensive effect.
Diuretics enhance antihypertensive effect.
Increase lithium levels and may cause lithum toxicity
Hyperkalemia with K and K sparing diuretics.
Risk of bone marrow suppression due to enalapril increased with concomittant use of immunosuppressives
Indication:
Refractory hypertension
Adverse Reaction:
Angioneurotic odema, nausea, headache,
cough, dizziness, fatigue, palpitations,
chest pain, fatigue, rash, Increase in BUN ,
serum K and creatinine levels may occur. Neutropenia,
Contra-Indications:
Hypersentivity to drug or components
history of angioedema, related to exposure to ACE inhibitor
Pregnancy
Special precautions-
Lactation
Renal & hepatic disease.
Congestive heart failure,
comcomittant K supplements & pot -conserving diuretics
Hypovalenic shock, diuretic therapy Periodic blood count monitoring to proclude neutropenia or agranulocytosis.
Dosages/ Overdosage Etc:
Indication
Refractory hypertension
Dosage
1 tab contains enalapril mal 5mg & amlodipine besyl 5mg- start with 1 tablet daily increase gradually acoording to response.
Elderly- 1/2 tab to start with and built up gradually with caution
Diuretics should be withheld forv2-3 days before starting combination.
Patient Information:
Take with or without food
Interaction with Food:
Take with or without food
Pregnancy and lactation:
Use contraindicated during pregnancy and lactation
