Antacids, sucralfate, calcium, Fe Zn prep reduce absorption of ciprofloxacin

Concurrent use with cicosporin may lead to tanscient increase in serum creatinine levels Increases in plasma levels and elimination of T12 of theophylline

Potentiates oral anticoagulant effects Disulpharam -like effect with alcohol

May affect metabolism of caffeine resulting in clearance of caffeine

Infections of urinary tract, respiratory tract,

infections of bone & joints,skin & skin structure,

Nausea, headache,

Vomiting, fatigue, abdominal pain,

Depression, dyspepsia

Constipation, dry mouth

Some times diarrhea Metallic taste, Urticaria,

Erythema and rashes

Rarely convulsions and haematogical changes

Severe hypersensitiviyt reactions

Hypersensitivity Patients with a history of blood dyscrasias

Special precautions-

Renal impairment History of seizures

Ensure adequate hydration and urinary output

Avoid alcohol ingestion

Not recommended for use in pegnancy and lactation

Not recommended for children Inadquate waterintake may cause to crystalluria

Indication-

Infections of urinary tract, respiratory tract, infections of bone & joints,skin & skin structure,

Dosage-

1 tab bid for 5- 10 days depending on severity and response

Not recommended for use during lactation and pregnancy

Not trecommended for use in children