Potentially Hazardous Interactions:

Resperine  -        Catecholamine-depleting drugs,such as resperine,may cause                   
  additive effects and precipitate marked hypotension or bradycardia.

Betablockers -   Betablockers may increase patients response to allergens

Adrenaline-  Reduce the effectiveness of usual doses of adrenaline in treating
   allergic reactions

Digitalis-            Risk of arrhythmias with digitalis.

Amiodrone, Quinidine-        Altered response to quinidine,amiodrone and possibly other
     antiarrhythmias.

Diabetics-         Glycemic control may be altered in diabetic patients.

Aminoglycosides, Lithium-    Hydrocholrthiazide may increase nephrotoxicity of                  amino-glycosides and lithium toxicity.

Toburamine-      Effects of tobucuraine may be prolonged

Coticosteroids-   Corticosteroids may increase risk of hypokalaemia.

 

Hypertension


 

Potentially life threatening Reactions:
Hypersensitvity,hypotension and severe bradycardia. Fluid and electrolytic  balance, dizziness headache, tiredness,depression, bradycardia, cold extremities.

Raynauld's type phenomena, congestive failure, reduced excercise  tolerance, dyspnoea,
bronchospasm, hypokalaemia, oedema, gout, impotence, pruritus. rash, nightmares, insomnia.

 

Second or third degree AV block,sinus bradycardia,cardio-genic shock,congestive failure,
lactation, hypersensitivity, bronchial asthma.

Special Precautions:
Renal or hepatic impairment,diabetes mellitus, hyperlipide-mia, hyperuricaemia, gout,
LVH and ventricular ectopics, thyro-toxicosis, major surgery, withdrawal.

 

Hypertension

1-2 tabs daily