CEFIZOX INJ
Manufacturer Details
GLAXO SMITH KLINE
Compositions:
Ceftizoxime sodium 250mg/500mg/1 g injection,
|
Strength
|
Rate
|
Packing Style
|
|
250mg
|
143.50
|
powder in vial
|
|
500mg
|
248.33
|
powder in vial
|
|
1g
|
394.23
|
powder in vial
|
List of Related Indications:
- Gonorrhoea
- Respiratory tract infection
- Septicaemia
- Skin & soft tissue infection
- Urinary tract infections- UTI
List Of Drugs:
- Ceftizoxime - Cephalosporins - @ Third generation( May 1990)
Indication Type Description:
Pharmacology/ Pharmacokinetics
Drug Interaction:
Drugs covered:
1st generation 2nd generation 3rd generation . Cephalexin Cefaclor Cefixime Cefadroxil Cefamandole Cefoperazone Cephadrine Cefotoxitin Cefotaxime Cephalothin Cefuroxime Ceftizoxime Cephapirin Cefonicid Ceftriaxone Cefazolin Cefmetazole Ceftazidime Cefotetan Ceftibuten Cefprozil Cefepime Cefpodoxime Loracarbef
Refer Cephalosporins
Renal clearance reduced by probenecid. Activity may be reduced by chloramphenicol. Interference with copper reduction method of testing glycosuria.
Indication:
A third generation drug.
Approved by (DCI) Drug Controller GENERAL - India For Marketing (Ref- IDMA Publication)
Name of Drug Indication Date of Approval
Ceftizomine Cephalosporin May 1990
Sodium
Drugs covered:
1st generation 2nd generation 3rd generation . Cephalexin Cefaclor Cefixime Cefadroxil Cefamandole Cefoperazone Cephadrine Cefotoxitin Cefotaxime Cephalothin Cefuroxime Ceftizoxime Cephapirin Cefonicid Ceftriaxone Cefazolin Cefmetazole Ceftazidime Cefotetan Ceftibuten Cefprozil Cefepime Cefpodoxime Loracarbef
Refer Cephalosporins
Adverse Reaction:
Anaphylactoid reactions.
On injection, burning, induration, tenderness, paraesthesia, phlebitis and cellulitis. Hypersens reactions.
Rash, pruritus or fever. Anorexia, nausea, vomiting, diarrhoea, rarely neutropenia, leucopenia and thrombocytopenia.
Transcient elevation of transaminases (SGOT and SGPT) and alkaline phosphatase, Transient rise in BUN and creatinine.
Contra-Indications:
Renal impairment, Htpensens to penicilins
Special precautions: Reports not available
Dosages/ Overdosage Etc:
A third generation drug.
Indications: Lower respiratory infections, urinary tract infections, gonorrhoea, pelvic inflamatory disease, intra-abdominal infections, septicaemia, skin and structure infections, bone & joint infections, meningitis.
Dosage: 1 to 2g every 8 to12 hours.
Children- More than 6mths - 50mg/kg every 6 to 8 hours. Dosage may be increased to 200/kg/day . Do not exceed the maximum adult dose for serious infection.
Storage: After reconstitution or dilution, solutions are stable for 24 hours or at temperature for 96 hours if reffrigerated at (5C. 41F).
Other Information:
For Availability/supplies
Contact -
1.Indian Drug Manufacturers Association (IDMA)
Phone- 022- 24944624/ 24974308
Fax- 022- 24950723
Email- idma@vsnl.com
Website: www.idma-assn.org
2.Bulk Drug Manufacturers Association (India)(BDMA)
Phone - 040-23703910/ 23706718
Fax- 040-23704804
Email- info@bdmai.org
Website: www.info@bdmai.org
Classifiaction: Antibiotic.
Patent position: Patent expires 13TH March, 1998
Major Brands:
CEFIZOX
GLAXO-WELLCOME
EPOCELIN RALLIS
Patient Information:
Refer cephalosporins
Pharmacology/ Pharmacokinetics:
Refer cephalosporins
Interaction with Food:
Refer cephalosporins
Pregnancy and lactation:
Refer cephalosporins
