Skeletal Muscle Relaxant include- Carisprodal, Chlorphenesin Maleate, Chlorzoxazone, Chlormezanone, Cyclobenzaprine, Methocarbinol, Metaxalone, Dantrolenes Sodium, Orphenadrine.

Indications:

Painful muscular skeletal conditions

Dosage:

The lethal dose orphendrine in adults is 2 to 3g Oral- 100mg each morning and evening. Do not crush or chew sustained release. Parentral- 60mg IV or IM. may be repeated every 12 hours..

Overdosage-

Symptoms Treatment The lethal dose orphenadrine in adults 2 3g .

1. Prevent futherabsorption by gastric lavage. Intoxification is very rapid and death can occur within

2. Hemodialysis may not be helpful. 3 to 5 hours preceded by deep coma,seizures and shock. Serious cardiac rhythm disturbances are common.

Missed dose-

1. If you miss a dose of this medicine, take it as soon as possible.

2. However, if it is almost time for next dose, skip the missed dose and go back to your regular dosing schedule.

3. Do not double doses.

Skeletal Muscle Relaxant include- Carisprodal, Chlorphenesin Maleate, Chlorzoxazone, Chlormezanone, Cyclobenzaprine, Methocarbinol, Metaxalone, Dantrolenes Sodium, Orphenadrine.

Refer Orphenadrine 

1.May cause drowsiness, blurred vision or fainting. Observe caution while driving or performing tasks requiring alertness,coordination or physical dexterity.

2. Avoid alcohol and CNS depressants.

3.May cause dry mouth, difficult urination, constipation, headache and GI upset. Notify physician if these persists or if skin rash or itching, rapid heart rate, palpitation or mental confusion occurs.

4. Allergy- Tell your doctr if you hadany unusual reactionto orphenadrine,food substances, preservatives, dyestuffs etc.

5. Pregnancy- Oephendrine hasnot been reported to cause birth defects or other problems in humans.

6. Breast feeding- Not known whether orphenadrine passes into breast milk. Not reported to cause problems in nursing babies.

7. Children- Studies done only in adults. No specific information comparing use of orphenadrine in children with use in other age groups.

8. Older adults- No specific information comparing use of orphenadrine in elderly

9. Other medicines- Tell your doctor if you taking any of the following- Alcohol or Central nervous system depressants or Tricyclic antidepressant - chance of side effects may be increased

10. Other medical problems- Tell your doctor if you have any of the following medicial problems- Disease of digestive tract -osephagus disease,stonachulcer,or intestinal blockage Enlarged prostrate or Fast or irregular heart beat or Glaucoma or Myasthenia gravis or Urinary tract blockage -orphenadrine has side effects that may be harmful to people with these conditions Heart disease or Kidney disease or Liver disease -chance of side effects may be increased

11. Missed dose - If you miss a dose of this medicine, take it as soon as possible. however, if it is almost time for the next dose, skip the missed dose. Do not double doses.

12. Storage - Keep out of reach of children. Store away from heat or direct sunlight. Do not store the capsule in bathroom, near the kitchen sink, or in other damp places.

13. Outdated medicines - Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of reach of children.

Reports not available.

Pregnancy:

It is not known whether orphenadrine can cause fetal harm or affect reproduction capacity. Use in pregnancy only when clearly needed.

Lactation:

It is not known whether orphenadrine is excreted in breast milk.

Children :

Safety and efficacy in use for children not been established. Not recommended in pediatric use.